Welcome to Shi Lab!

Pushing the frontiers of bio-optical imaging and profiling

Methodology development and application of vibrational spectroscopy and imaging for understanding the spatiotemporal organizations of biological systems.

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Label-free SRS imaging of mouse brain

Label-free SRS imaging of mouse brain

SRS volumetric imaging of whole zebrafish

SRS volumetric imaging of whole zebrafish

SRS-fluorescence tandem imaging on protein (magenta), lipids (green) and vascular network (red).

SRS-fluorescence tandem imaging on protein (magenta), lipids (green) and vascular network (red).

FTIR imaging of mouse brain

FTIR imaging of mouse brain

epr-SRS imaging of alpha-tubulin in COS7 cells

epr-SRS imaging of alpha-tubulin in COS7 cells

3D epr-SRS imaging of GFAP in mouse brain

3D epr-SRS imaging of GFAP in mouse brain

3D highly-multiplexed protein imaging

3D highly-multiplexed protein imaging

High-throughput single-cell metabolic profiling

High-throughput single-cell metabolic profiling